Lancet)子刊物《The
Lancet
Regional
Health》刊載文獻表明,適度飲用含有咖啡因成分的咖啡或茶飲,有助於降低遺傳風險較高的亞洲人,晚年罹患帕金森氏症的風險。
喝咖啡有助預防帕金森氏症? 《刺絡針》:無攝取者患病率飆8倍
咖啡因為何降帕金森氏症風險?
專家解答:降低3種LRRK2基因表現
,為一種基因表現)」以發揮神經保護作用有關。另外,不同變異體的突變會透過相異機制對LRRK2蛋白產生影響:
突變導致「細胞週期素依賴性激酶5」(Cdk5)磷酸化增加,進而增加激酶活性,導致神經元死亡。
咖啡適量喝對身體好處多?
有望預防失智、心臟病、憂鬱症
資料來源:
Coffee
for
Cardioprotection
and
Longevity
Coffee
and
Lower
Risk
of
Type
2
Diabetes:
Arguments
for
a
Causal
Relationship
The
Effect
of
Caffeine
on
the
Risk
and
Progression
of
Parkinson’s
Disease:
A
Meta-Analysis
Caffeine
intake
interacts
with
Asian
gene
variants
in
Parkinson’s
disease:
a
study
in
4488
subjects
Synergistic
neuroprotection
by
coffee
components
eicosanoyl-5-hydroxytryptamide
and
caffeine
in
models
of
Parkinson’s
disease
and
DLB
Association
between
dietary
caffeine,
coffee,
and
tea
consumption
and
depressive
symptoms
in
adults:
A
systematic
review
and
dose-response
meta-analysis
of
observational
studies
交互作用傷身! 咖啡不能與哪些藥品一起服用? 藥師點名兩類人最好少喝
咖啡不是每個人都能喝? 研究:身體出現「1基因」突變 喝3杯就有腎衰竭風險